AffinityDNA Dog Multidrug Resistance 1 (MDR1) DNA Test | Home Sample Collection for 1 Canine | Puppy MDR1 Testing | Results in 7 Working Days | Complete Kit With No Extra Fees

• MULTIDRUG RESISTANCE 1 DNA TEST: It is an accurate, convenient, & affordable tool to help breeders avoid producing Multidrug Resistance 1 (MDR1) carrier & affected offspring & significantly reduce the gene frequency in future generations (NOT A BREED TEST).
• HEALTH TEST FOR YOUR PET: The test identifies whether the tested dog has inherited the mutated ABCB1 gene & reports one of three possible outcomes – Clear, Carrier or Affected
• SIMPLE & EASY SAMPLE COLLECTION: Samples can be collected simply & painlessly using the supplied cheek swabs. Results issued by email 7 working days after receipt of samples
• COMPLETE TESTING KIT: The DNA Sample Collection Kit contains 4 x sterile mouth swabs (all 4 for 1 dog), step-by-step sample collection instructions, registration form & return envelope.
• ABOUT US: AffinityDNA is an industry-leading DNA Testing company with more than 15 years’ experience in the DNA business & established partnerships with some of the most highly accredited DNA testing laboratories in the world.

Product description Multidrug Resistance 1 is inherited as an autosomal incomplete dominant disease. The MDR1 gene codes for the production of a protein known as p-glycoprotein. P-glycoprotein acts as a pump that removes certain drugs and toxins from the body. A mutation in the ABCB1 gene associated with MDR1 prohibits P-glycoprotein’s ability to limit absorption, distribution, and excretion of drugs and allows higher levels of drugs to enter the brain. Dogs only need to inherit one copy of the MDR1 mutation to be at risk for sensitivity to certain drugs. Dogs with two copies of the MDR1 mutation can have more severe reactions such as excess salivation, tremors, anorexia, blindness and possibly death. MDR1 affected dogs are at risk of developing neurologic symptoms from several common drugs and you should inform your veterinarian if your dog is a MDR1-carrier or MDR1-affected so they can adjust dosage or provide an alternative medication. The DNA test is an accurate, convenient, and affordable tool to help breeders avoid producing Multidrug Resistance 1 carrier and affected offspring and significantly reduce the gene frequency in future generations. This test is available for all dog breeds. The results confirm 1 of the 3 possible genotypes for the tested dog: CLEAR (those having two genes from their parents that are mutation free and will not be affected by MDR1). CARRIER (those having one normal copy of the MDR1 gene, and one mutation. This means that the dog has an increased risk of drug sensitivity). AFFECTED (those having two copies of the mutated MDR1 gene from their parents and are at risk of adverse drug reactions). Ingredients The DNA Sample Collection Kit Contains - 4 x sterile mouth swabs (all 4 for 1 dog), step-by-step sample collection instructions, registration form and return envelope. Directions Hold the dog’s head firmly against your body with one hand. With the other hand, insert the swab into the dog’s mouth and place it against the inside surface of the cheek. Firmly rub the swab against the inside of the cheek, rotating the swab for about ten seconds. The objective is to collect loose cheek cells, NOT saliva. Please contact us with any questions. Legal Disclaimer The test identifies whether the tested dog has inherited the mutated ABCB1 gene associated with MDR1 and reports one of three possible outcomes – Clear, Carrier or Affected. It is not an ancestry test, breed test or parentage test. It is for Multidrug Resistance 1 MDR1 only.